Can Zantac Cause Uterine Cancer?

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If you're a former Zantac user and have been diagnosed with uterine cancer, you may be wondering - could my uterine cancer be caused by Zantac? One of the world's most popular heartburn drugs may have dangerously high levels of a probable cancer-causing chemical, according to the FDA. Zantac (ranitidine) medications are being recalled from pharmacies due to the possibility that there is a link between the use of this medication and several types of cancer. Some cancer sufferers who have used Zantac have begun exploring taking legal action against the manufacturers of Zantac.

What Are The Symptoms of Uterine Cancer?

Different patients may experience different symptoms of uterine cancer and these symptoms can change as the cancer progresses. There are also some other health conditions that can cause similar symptoms.

Some of the most common symptoms of uterine cancer include:

• Abnormal vaginal bleeding
• Unusual vaginal discharge
• Painful intercourse
• Pelvic pain or pressure
• Painful urination, trouble urinating, or blood in the urine
• Painful or difficult bowel movements, blood in the stool
• Bleeding from rectum or bladder
• Fluid buildup in the abdomen or the legs
• Trouble breathing
• Lack of appetite
• Weight loss

Types of Uterine Cancer (Endometrium Cancer)

Uterine (endometrium) cancer most commonly starts in the uterine lining, otherwise known as the uterine wall, which is also called by the medical term "endometrium".

There are four main types of uterine cancer:

• Endometrial adenocarcinoma - This is the most common form of uterine cancer and begins in the glands of the uterine wall. These account for approximately 80% of uterine cancers and vary in severity.
• Adenosquamous carcinoma - About 10 percent of uterine cancers are adenosquamous. This cancer is comprised of squamous cells and gland-like cells.
• Papillary serous carcinoma - Representing 5 percent of uterine cancers, this is an aggressive cancer that often resurfaces.
• Uterine sarcoma - This cancer develops in the uterine muscle wall (myometrium). About 5% of uterine cancers are uterine sarcoma.

What Are The Risk Factors of Uterine Cancer?

There are a few different factors that may increase the risk of uterine cancer, such as:

• Being older than 50 years old
• Obesity
• Taking estrogen alone (without progesterone) for hormone replacement during menopause
• Past issues getting pregnant
• Fewer than 5 periods in a year before menopause
• Use of tamoxifen - a breast cancer drug
• Family history of uterine, colon, or ovarian cancer

While not yet conclusively proven, there is reason to suspect that Zantac users could also be at a higher risk of developing uterine cancer due to the presence of a probable carcinogen at high levels in the drug.

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